BOF: General (Paediatrics)
Which of the following is NOT a reasonable treatment strategy for chronic granulomatous disease? a) Allogeneic haematopoietic stem cell...
EMQ: Malignant (Myeloproliferative Disease)
For each of the following clinical scenarios (1-5) choose the SINGLE diagnosis from the list below (a-h) to which the scenario best fits....
BOF: Clotting (Anticoagulation)
Which ONE of the following statements (a-e) regarding activated protein C is TRUE? a) Activated following cleavage by thrombomodulin b)...
BOF: Transfusion (Plasma Products)
Therapeutic plasma exchange and intravenous immunoglobulin are often used for the same indications, and each may be unavailable due to...
BOF: General (Haemoglobinopathy)
Transfusion should be used selectively in sickle cell disease to avoid the risk of transfusion reaction, allo-immunisation and iron...
BOF: Malignant (Myeloproliferative Disorder)
A 59 year old man is known to have a JAK2 V617F mutated polycythaemia. He has been maintained on a venesection programme for the last 6...
BOF: Clotting (Haemophilia)
A 12 year old boy presents with recurrent epistaxis. Blood results show Hb 12 g/dL, Plts 170 x 10⁹/L, APTT ratio 1.5, INR 1.1, FVIIIc...
BOF: Transfusion (Red Cell Serology)
For the routine antibody screen prior to blood transfusion, which ONE of the following red cell antigens can be expressed either...
BOF: General (Haemoglobinopathy)
Which ONE of the following complications of paediatric sickle cell disease has been shown to be reduced by the use of hydroxyurea from...
BOF: Malignant (Supportive Care)
According to recent guidelines , which ONE of the following patients should not receive antifungal prophylaxis? a) 18 year old woman...
