BOF: General (Paediatrics)
- Sep 5, 2016
- 1 min read
A 2 year old child with Diamond Blackfan anaemia (DBA) is to be started on a dose of 2mg/kg of prednisolone for an exacerbation of anaemia. Which ONE of the following strategies (a-e) would you consider to be LEAST appropriate
a) Bisphosphonates to prevent secondary osteoporosis
b) Blood transfusion
c) Hepatitis B immunisation
d) Trimethoprim-sulphamethoxazole for Pneumocystis jiroveci prophylaxis
e) Varicella immunisation
Answer:
a) Bisphosphonates to prevent secondary osteoporosis
Explanation:
Bisphosphonates are not currently recommended for prevention of secondary osteoporosis in DBA patients on long term or high dose steroids although avascular necrosis of the femoral head remains a complication. Varicella and hepatitis B immunisation are recommended prior to commencing therapy and Pneumocystis prophylaxis for prolonged or high dose steroid courses.
Reference:
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